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    Recombinant Human sDLL-4
    品牌：PeproTech
    货号：140-07-100ug 规格：100ug 目录价：￥11600
    货号：140-07-1mg 规格：1mg 目录价：￥51397
    货号：140-07-250ug 规格：250ug 目录价：￥22431
    货号：140-07-25ug 规格：25ug 目录价：￥2910
    货号：140-07-500ug 规格：500ug 目录价：￥33338
    货号：140-07-5ug 规格：5ug 目录价：￥1169
    产品详情
    产品名称:
    Recombinant Human sDLL-4
    别名:
    soluble DLL-4, Delta-like protein 4, Drosophila Delta homolog 4
    产品描述:
    Human sDLL-4 comprises the extracellular signaling domain of DLL, a member of a structurally-related family of single-pass type I transmembrane proteins that serve as ligands for Notch receptors. DLL-4 functions to specifically activate the Notch-1 and Notch-4 receptors. The Notch signaling pathway regulates endothelial cell differentiation, proliferation and apoptosis, and is essential for the development, maintenance and remodeling of the vascular system. Targeted deletion of the DLL-4 gene in mice resulted in severe vascular defects and death before birth. Up-regulation of DLL-4 expression has been implicated in the vascular development of certain tumors. The human DLL-4 gene consists of a 503 amino acid extracellular domain with one DSL domain, eight EGF-like repeats, a 21 amino acid transmembrane domain, and a 135 amino acid cytoplasmic domain. Recombinant Human sDLL-4 is a 54.3 kDa glycoprotein containing 498 amino acid residues.
    宿主来源:
    HEK293 cells
    推荐稀释度:
    请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
    预期分子量:
    54.3 kDa
    产品形式:
    Bulk
    产地:
    美国
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