官网链接
折扣/货期| 货号：300-10H-100ug | 规格：100ug | 目录价：￥22138 |
| 货号：300-10H-10ug | 规格：10ug | 目录价：￥2836 |
| 货号：300-10H-1mg | 规格：1mg | 目录价：￥88652 |
| 货号：300-10H-250ug | 规格：250ug | 目录价：￥38710 |
| 货号：300-10H-2ug | 规格：2ug | 目录价：￥1163 |
| 货号：300-10H-500ug | 规格：500ug | 目录价：￥57513 |
| 货号：300-10H-50ug | 规格：50ug | 目录价：￥13268 |
产品详情
产品名称:
Recombinant Human Oncostatin M (196 a.a.)
别名:
OSM
产品描述:
Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi's sarcoma cells, OSM can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi's sarcoma cells, but inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL-6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptors in hepatoma cells. OSM shares several structural and functional characteristics with LIF, IL-6, and CNTF. Human OSM is active on murine cells. The human OSM gene encodes for a 252 amino acid polypeptide, containing 25 amino acid signal sequence for secretion and a 227 precursor protein. Proteolytic processing of this precursor removes an 18 amino acid C-terminal peptide, and generates the mature OSM form. PeproTech's Recombinant Human Oncostatin M (196 a.a.) is a HEK293 cell-derived, 196 amino-acid length glycoprotein that has a calculated theoretical molecular weight of 22.2 kDa, but migrates at an apparent molecular weight of 32-34 kDa by SDS-PAGE analysis under reducing conditions due to glycosylation.
宿主来源:
HEK293 cells
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
22.2 kDa
产品形式:
Bulk
产地:
美国
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