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折扣/货期| 货号：200-13A-100ug | 规格：100ug | 目录价：￥22246 |
| 货号：200-13A-10ug | 规格：10ug | 目录价：￥2850 |
| 货号：200-13A-1mg | 规格：1mg | 目录价：￥89085 |
| 货号：200-13A-250ug | 规格：250ug | 目录价：￥38900 |
| 货号：200-13A-2ug | 规格：2ug | 目录价：￥1169 |
| 货号：200-13A-500ug | 规格：500ug | 目录价：￥57794 |
产品详情
产品名称:
Recombinant Human IL-13 Variant
别名:
None
产品描述:
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1beta, TNF-alpha, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching, resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and murine IL-13 are cross-species reactive. A variant of IL-13 shows enhanced functional activity compared with the wild type IL-13. PeproTech's genetic variant, termed Recombinant Human IL-13 Variant, is a mature 115 amino acid protein with a substitution of Q for R at position 113. The calculated molecular weight of Recombinant Human IL-13 Variant is 12.6 kDa.
宿主来源:
E.coli
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
12.6 kDa
产品形式:
Bulk
产地:
美国
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