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    Recombinant Human IGF-BP7
    品牌:PeproTech
    货号:350-09-100ug 规格:100ug 目录价:¥11600
    货号:350-09-1mg 规格:1mg 目录价:¥51397
    货号:350-09-250ug 规格:250ug 目录价:¥22431
    货号:350-09-25ug 规格:25ug 目录价:¥2910
    货号:350-09-500ug 规格:500ug 目录价:¥33338
    货号:350-09-50ug 规格:50ug 目录价:¥7870
    货号:350-09-5ug 规格:5ug 目录价:¥1169
    产品详情
    产品名称:
    Recombinant Human IGF-BP7
    别名:
    Insulin-like Growth Factor-Binding Protein 7, IBP-7, Mac25, IGF binding protein related protein-1 (IGFBP-rP1)
    产品描述:
    IGF-BPs control the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently, there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP7 is expressed in a wide range of normal human tissues, and it generally shows reduced expression in cancer cell lines of prostate, breast, colon, and lung origin. It plays a role in skeletal myogenesis by binding to IGF in a manner that inhibits IGF-induced differentiation of skeletal myoblasts, without affecting IGF-induced proliferation. Additionally, IGF-BP7 suppresses growth and colony formation of prostate and breast cancer cell lines through an IGF-independent mechanism, which causes a delay in the G1 phase of the cell cycle and increased apoptosis. Recombinant Human IGF-BP7 is a 26.4 kDa protein consisting of 256 amino acid residues.
    宿主来源:
    E.coli
    推荐稀释度:
    请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
    预期分子量:
    26.4 kDa
    产品形式:
    Bulk
    产地:
    美国
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