货号:100-05-100ug | 规格:100ug | 目录价:¥11590 |
货号:100-05-1mg | 规格:1mg | 目录价:¥51397 |
货号:100-05-250ug | 规格:250ug | 目录价:¥22409 |
货号:100-05-25ug | 规格:25ug | 目录价:¥2910 |
货号:100-05-500ug | 规格:500ug | 目录价:¥33306 |
货号:100-05-5ug | 规格:5ug | 目录价:¥1169 |
产品详情
产品名称:
Recombinant Human IGF-BP5
别名:
Insulin-like Growth Factor-Binding Protein 5, IBP-5
产品描述:
IGF-BPs control the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently, there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP5 is a 28.6 kDa, cysteine-rich, secreted protein produced by vascular smooth muscle cells. It is the major IGF-binding protein present in bone tissue and helps potentiate the action of IGF-I on smooth muscle cells, fibroblasts, and osteoblasts. Data shows that IGFBP-5 acts as a growth inhibitor and pro-apoptotic agent in breast cancer cells. IGFBP-5-overexpressing mice show an increase in neonatal mortality, reduced female fertility, whole-body growth inhibition, and retarded muscle development. Recombinant Human IGF-BP5 is a 28.6 kDa protein consisting of 253 amino acid residues.
宿主来源:
E.coli
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
28.6 kDa
产品形式:
Bulk
产地:
美国
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