货号:100-15R-100ug | 规格:100ug | 目录价:¥16593 |
货号:100-15R-10ug | 规格:10ug | 目录价:¥2836 |
货号:100-15R-1mg | 规格:1mg | 目录价:¥66482 |
货号:100-15R-250ug | 规格:250ug | 目录价:¥29043 |
货号:100-15R-2ug | 规格:2ug | 目录价:¥1163 |
货号:100-15R-500ug | 规格:500ug | 目录价:¥43140 |
产品详情
产品名称:
Recombinant Human EGF Receptor (EGFR)
别名:
ErbB1
产品描述:
EGF Receptor (EGFR, ErbB1) is a transmembrane protein that exerts tyrosine kinase activity upon ligand-induced activation. EGFR can be activated by binding EGF, or at least six other structurally related protein ligands, including TGF-alpha, HB-EGF,Betacellulin (BTC), Amphiregulin, Epiregulin, and Epigen. Upon activation, EGFR initiates a signaling cascade, which includes dimerization and internalization, tyrosine phosphorylation, DNA synthesis of target genes and, ultimately, cell proliferation. EGFR signaling plays a role in the growth and differentiation of normal cells, but elevated EGFR activity is correlated with the development and pathogenesis of certain cancers. Recombinant soluble Human EGFR is a 621 amino acid glycoprotein comprising the extracellular domain of EGFR, and migrates at an apparent MW of 97.5 kDa by SDS-PAGE analysis under reducing conditions.
宿主来源:
CHO cells
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
68.6 kDa
产品形式:
Bulk
产地:
美国
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