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Recombinant Human CTGF
品牌:PeproTech
货号:120-19-100ug 规格:100ug 目录价:¥15010
货号:120-19-1mg 规格:1mg 目录价:¥66482
货号:120-19-20ug 规格:20ug 目录价:¥2900
货号:120-19-250ug 规格:250ug 目录价:¥29043
货号:120-19-500ug 规格:500ug 目录价:¥43140
货号:120-19-5ug 规格:5ug 目录价:¥1163
产品详情
产品名称:
Recombinant Human CTGF
别名:
Connective Tissue Growth Factor, CCN2, Hypertrophic chondrocyte-specific protein 24 (HCS24)
产品描述:
CTGF is a member of the CCN family of secreted cysteine-rich regulatory proteins, and is the major mitogenic and chemoattractant protein produced by umbilical vein and vascular endothelial cells. CTGF stimulates the proliferation and differentiation of chondrocytes, induces angiogenesis, promotes cell adhesion of fibroblasts, endothelial and epithelial cells, and binds to IGF, TGF-beta1 and BMP-4. Cell migration and adhesion are signaled through binding to specific cell surface integrins and to heparin sulfate proteoglycans. CTGF (98 a.a.), a lower molecular weight isoform containing the C-terminal portion of the full length CTGF protein, exerts full heparin binding, cell adhesion, and mitogenic CTGF activity. Mature Human CTGF is a 38.0 kDa secreted protein containing 323 amino acid residues. CTGF is comprised of four distinct structural domains (modules), which are identified as IGF-Binding Protein (IGF-BP), von Willebrand Factor C (VWFC), Thrombospondin type I (TSP type I), and C-terminal cysteine knot-like (CTCK) domains. Full length CTGF can be proteolytically cleaved in certain tissues to yield N-terminal truncated isoforms, which, depending on the isoform, contain only the TSP type I and CTCK domains or contain only the CTCK domain. Recombinant Human CTGF is an 11.0 kDa protein consisting of 97 amino acid residues.
宿主来源:
E.coli
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
11 kDa
产品形式:
Bulk
产地:
美国
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