Recombinant Human C1 Inhibitor-细胞因子、趋化因子与生长因子-ELISA_抗体_蛋白_核苷酸

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Recombinant Human C1 Inhibitor

品牌：PeproTech

官网链接

说明书

折扣/货期

货号：130-20-1mg	规格：1mg	目录价：￥13709
货号：130-20-200ug	规格：200ug	目录价：￥2850
货号：130-20-500ug	规格：500ug	目录价：￥8892
货号：130-20-50ug	规格：50ug	目录价：￥1169

产品详情

产品名称:

Recombinant Human C1 Inhibitor

别名:

Plasma protease C1 inhibitor, C1inh, C1 Esterase Protein, C1-inhibiting factor, Serpin G1

产品描述:

C1 inhibitor is a member of the serpin family of structurally related proteins, and is the primary regulator of the immune complement system. C1 inhibitor is a protease inhibitor that functions to inhibit the complement system in order to prevent over-activation or spontaneous activation. Inhibition is achieved by binding to and irreversibly inhibiting the C1r and C1s proteases of the C1 complex, which has the effect of shutting down all subsequent downstream events in the complement activation cascade. C1 inhibitor can also inhibit various other proteases, including Kallikrein, Factor XIa, and Factor XIIa. Deficiencies in C1 inhibitor are the primary cause of hereditary angioedema (HAE, hereditary angioneurotic edema), a disease characterized by edema in the respiratory and gastrointestinal tracts. In certain clinical situations, the direct administration of C1 inhibitor can be used to treat HAE and certain other conditions. Recombinant Human C1 Inhibitor is a highly glycosylated glycoprotein containing 478 amino acid residues (52.8kDa), corresponding to amino acids 23-500 of the C1 inhibitor precursor, and is fully functional in its ability to inhibit the C1 complex. Glycosylated C1 Inhibitor migrates at an apparent molecular weight of approximately 80-90 kDa by SDS PAGE analysis under reducing conditions.

宿主来源:

CHO cells

推荐稀释度:

请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度

预期分子量:

52.8 kDa

产品形式:

Bulk

产地:

美国

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