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    Recombinant Human ApoE4
    品牌：PeproTech
    货号：350-04-100ug 规格：100ug 目录价：￥1183
    货号：350-04-1mg 规格：1mg 目录价：￥5966
    货号：350-04-500ug 规格：500ug 目录价：￥2836
    产品详情
    产品名称:
    Recombinant Human ApoE4
    别名:
    Apolipoprotein E4
    产品描述:
    ApoE belongs to a group of proteins that bind reversibly with lipoprotein and play an important role in lipid metabolism. In addition to facilitating solubilization of lipids, these proteins help to maintain the structural integrity of lipoproteins, serve as ligands for lipoprotein receptors, and regulate the activity of enzymes involved in lipid metabolism. Significant quantities of ApoE are produced in the liver and brain, and to some extent in almost every organ. ApoE is an important constituent of all plasma lipoproteins. Its interaction with specific ApoE receptor enables uptake of chylomicron remnants by liver cells, which is an essential step during normal lipid metabolism. It also binds with the LDL receptor (apo B/E). Defects in ApoE are a cause of hyperlipoproteinemia type III. ApoE exists in three major isoforms; E2, E3, and E4, which differ from one another by a single amino-acid substitution. Individuals heterozygous for the ApoE4 allele are at higher risk of late-onset Alzheimer's disease. Recombinant Human ApoE4 is a 34.4 kDa protein containing 300 amino acid residues.
    宿主来源:
    E.coli
    推荐稀释度:
    请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
    预期分子量:
    34.4 kDa
    产品形式:
    Standard
    产地:
    美国
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