官网链接
折扣/货期| 货号：130-07-100ug | 规格：100ug | 目录价：￥16430 |
| 货号：130-07-1mg | 规格：1mg | 目录价：￥89085 |
| 货号：130-07-20ug | 规格：20ug | 目录价：￥2910 |
| 货号：130-07-250ug | 规格：250ug | 目录价：￥38900 |
| 货号：130-07-500ug | 规格：500ug | 目录价：￥57794 |
| 货号：130-07-5ug | 规格：5ug | 目录价：￥1169 |
产品详情
产品名称:
Recombinant Human ANG-2
别名:
Angiopoietin-2, ANGPT2
产品描述:
ANG-2 binds to the endothelial cell specific receptor Tie-2, but, in contrast to ANG-1, does not induce tyrosine phosphorylation. Consequently, ANG-2 modulates ANG-1 activation of Tie-2 and, depending on the physiological and biochemical environment, can act either as an agonist or antagonist of Tie-2 induced angiogenesis. The signaling interactions of ANG-1, ANG-2 and Tie-2, along with less characterized ANG-3 and ANG-4, are required for embryonic and adult angiogenesis. Physiologically, ANG-1 and ANG-2 are associated with sprouting, tube formation, and structural integrity of newly formed blood vessels. Mature human ANG-2 is a secreted protein containing 480 amino acid residues. ANG-2 is composed of an alpha-helix-rich "coiled coil" N-terminal domain and fibrinogen-like C-terminal domain. ANG-2 exists predominantly in the form of a disulfide-linked dimer. Recombinant Human ANG-2 is a C-terminal histidine-tagged glycoprotein which migrates with an apparent molecular mass of 60.0-70.0 kDa by SDS-PAGE under reducing conditions. Sequencing analysis shows an N-terminal sequence starting with residue 68 (D) of the ANG-2 precursor protein. The calculated molecular weight of Recombinant Human ANG-2 is 50.1 kDa.
宿主来源:
CHO cells
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
50.1 kDa
产品形式:
Bulk
产地:
美国
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