货号:450-24-100ug | 规格:100ug | 目录价:¥13470 |
货号:450-24-1mg | 规格:1mg | 目录价:¥88652 |
货号:450-24-250ug | 规格:250ug | 目录价:¥37196 |
货号:450-24-25ug | 规格:25ug | 目录价:¥2900 |
货号:450-24-500ug | 规格:500ug | 目录价:¥57513 |
货号:450-24-5ug | 规格:5ug | 目录价:¥1163 |
产品详情
产品名称:
Recombinant Human Adiponectin
别名:
Acrp-30, GBP-28, APM-1, Gelatin-binding protein, AdipoQ
产品描述:
Adiponectin is an adipose-derived secreted protein containing 226 amino acid residues. It is relatively abundant in humans and rodents, accounting for about 0.01% of total plasma protein. The circulating levels of adiponectin are decreased under conditions of obesity, insulin resistance, and type II diabetes. Disruption of adiponectin in mice causes insulin resistance and neointimal formation. Conversely, administration of recombinant adiponectin suppresses hepatic glucose production, and reverses insulin resistance associated with both lipoatrophy and obesity. The protective role of adiponectin is attributed to its anti-inflammatory properties (e.g. ability to suppress expression of TNF-alpha and class A scavenger receptor in macrophages). Recombinant Human Adiponectin is a multimeric glycoprotein containing amino acids Glu-19 to Asn-244 of the adiponectin precursor protein fused to an N-terminal histidine tag. Monomeric glycosylated adiponectin migrates at an apparent molecular weight of approximately 35.0 kDa by SDS PAGE analysis under reducing conditions. The calculated molecular weight of Recombinant Human Adiponectin is 25.9 kDa.
宿主来源:
Hi-5 Insect cells
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
25.9 kDa
产品形式:
Bulk
产地:
美国
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