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Protein Phosphatase 2A C subunit (L309 deletion mutant; human, recombinant)
货号：10011237 规格：10 µg 目录价：￥4018
产品详情
产品名称:
Protein Phosphatase 2A C subunit (L309 deletion mutant; human, recombinant)
别名:
PP2A Cα|PP2A L309|PP2A Δ309
产品描述:
Reversible protein phosphorylation is a fundamental regulatory mechanism in all aspects of biology. Protein phosphatase 2A (PP2A) is a divalent cation-independent protein serine/threonine phosphatase involved in regulating numerous cellular processes including the cell cycle, growth and differentiation and is also thought to be a potential tumor suppressor.{15392} PP2A is a hetrotrimeric protein containing a 65 kDa scaffolding A subunit, a regulatory B subunit and a 36 kDa catalytic C subunit.{15393} The recombinant PP2A catalytic subunit has the characteristic properties of Type 2A phosphatases and is highly sensitive to okadaic acid and microcystins.{15391} The provided preparation of the catalytic subunit of PP2A is useful for the study of enzyme kinetics and regulation, to dephosphorylate target substrates and to evalsuate the effects of test substances on the activity of the phosphatase.
保存温度:
-80
运输温度:
-80
产品形式:
20 mM Tris, pH 7.5, with 100 mM sodium chloride, 5 mM MgCl2, 1 mM EDTA, and 25% glycerol
有效期:
365
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