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折扣/货期| 货号：14012-1 mg | 规格：1 mg | 目录价：￥868 |
| 货号：14012-10 mg | 规格：10 mg | 目录价：￥6202 |
| 货号：14012-5 mg | 规格：5 mg | 目录价：￥3556 |
| 货号：14012-500 µg | 规格：500 µg | 目录价：￥462 |
产品详情
产品名称:
Prostaglandin E2 Ethanolamide
别名:
Dinoprostone Ethanolamide|PGE2-EA|Prostamide E2
产品描述:
Prostaglandin E2 ethanolamide (PGE2-EA) is an analog of PGE2 (Item No. 14010) with improved water solubility and stability. PGE2-EA is formed via COX-2 metabolism of arachidonoyl ethanolamide (AEA; Item No. 90050) and acts as an agonist at E prostanoid (EP) receptors 1-4 (Kis = 2.45, 0.46, 0.2, and 0.51 μM, respectively).{11045,10926} It also inhibits indoleamine 2,3-dioxygenase-1 (IDO-1) in THP-1 cells and human monocytes (IC50s = 5.7 and 4.7 μM, respectively).{40333} PGE2-EA (10 μM) prevents morphological changes and F-actin rearrangement as well as reduces L-homocysteine-induced NLRP3 inflammasome formation and activation in podocytes.{41626} Ex vivo, PGE2-EA reduces luminal damage and lymphocyte infiltration in a human mucosal explant colitis model.{41627}
保存温度:
-20
运输温度:
-20
预期分子量:
395.5
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
194935-38-1
分子式:
C22H37NO5
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