官网链接
折扣/货期| 货号：13010-1 mg | 规格：1 mg | 目录价：￥308 |
| 货号：13010-10 mg | 规格：10 mg | 目录价：￥1778 |
| 货号：13010-5 mg | 规格：5 mg | 目录价：￥1246 |
| 货号：13010-50 mg | 规格：50 mg | 目录价：￥7980 |
产品详情
产品名称:
Prostaglandin E1
别名:
Alprostadil|NSC 165559|PGE1
产品描述:
Prostaglandin E1 (PGE1) is a vasoactive prostaglandin and an active metabolite of dihomo-γ-linolenic acid (DGLA; Item No. 90230).{64886,10906} It is formed from DGLA by COX-1 and COX-2. PGE1 is an agonist of the PGE2 (Item No. 14010) receptor subtypes EP1, EP2, EP3, and EP4, and the IP receptor (Kis = 36, 10, 1.1, 2.1, and 33 nM, respectively, for the mouse receptors).{6640} It inhibits ADP-induced platelet aggregation of isolated human platelet-rich plasma (IC50 = 40 nM) and isoproterenol-induced increases in L-type calcium current (ICa) in isolated rabbit atrial cells (EC50 = 27 nM).{960,9061} PGE1 (100 nM) induces vasodilation in isolated rat aortic rings and activates ATP-sensitive potassium channels (KATP) in a cell-attached patch clamp assay using isolated rat vascular smooth muscle cells (VSMCs).{64886} It decreases femoral arterial perfusion pressure in dogs.{1350} Formulations containing PGE1 have been used in the treatment of erectile dysfunction and to maintain patency of the ductus arteriosesus in neonates with congenital heart defects who depend on a patent ductus arteriosesus for survival.
保存温度:
-20
运输温度:
-20
预期分子量:
354.5
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
745-65-3
分子式:
C20H34O5
您可能感兴趣的产品
Prostaglandin E2
货号：AG-CL1-0001-M001
5-trans-17-phenyl trinor Prostaglandin F2α
货号：9003836-1 mg
Prostaglandin A2 ethyl ester
货号：9002816-1 mg
Prostaglandin D2 Dopamine
货号：9002504-1 mg
Prostaglandin E1 ethyl ester
货号：9001730-1 mg
Prostaglandin E1 isopropyl ester
货号：9001729-1 mg
Prostaglandin D2 Ethanolamide-d4
货号：9001413-100 µg
Prostaglandin E2 Ethanolamide-d4
货号：9001412-100 µg
促销活动
相关产品推荐
