货号:35204-10 mg | 规格:10 mg | 目录价:¥1610 |
货号:35204-25 mg | 规格:25 mg | 目录价:¥3346 |
货号:35204-5 mg | 规格:5 mg | 目录价:¥868 |
货号:35204-50 mg | 规格:50 mg | 目录价:¥6272 |
产品详情
产品名称:
PAR2 (1-6) amide (human) (trifluoroacetate salt)
别名:
SLIGKV-NH2
产品描述:
PAR2 (1-6) amide is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR2 and residues 37-42 of the full-length sequence.{61701} It binds to NCTC 2544 cells expressing human PAR2 (Ki = 9.64 µM in a radioligand binding assay) and induces calcium mobilization in the same cells (EC50 = 0.075 µM).{61702} PAR2 (1-6) amide (100 µM) reduces colony formation of A549 lung cancer cells.{61701} It induces superoxide production and degranulation in isolated human eosinophils when used at a concentration of 500 µM.{50355} PAR2 (1-6) amide (5 µmol/kg) induces tear secretion in rats when used in combination with amastatin (Item No. 16719).{61703}
保存温度:
-20
运输温度:
-20
预期分子量:
614.8
产品形式:
A solid
有效期:
1460
纯度:
≥95%
CAS号:
2379569-17-0
分子式:
C28H54N8O7 • XCF3COOH
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