货号:10004806 | 规格:1 ea (100 µg) | 目录价:¥4410 |
产品详情
产品名称:
p53 Monoclonal Antibody (Clone BP53-12)
别名:
Antigen NY-CO-13|Cellular Tumor Antigen p53|Phosphoprotein p53|Transformation-related Protein 53|Tumor Protein p53|Tumor Suppressor p53
产品描述:
Epitope: Binds to N-terminal amino acids 16-25 of wild-type and mutant p53 Cellular p53, often called the 'guardian of the genome,' is a transcription factor that is activated in response to cellular stress (DNA damage, hypoxia, heat shock, etc.) and acts to prevent further proliferation of the stressed cell by induction of cell cycle arrest or apoptotic mediators.{8237} Nearly 50% of human tumors have mutated or non-functional p53. This antibody is suitable for a variety of techniques to distinguish between p53 positive and p53 negative tumors.{11929} This antibody binds the N-terminal (amino acids 16-25) of wild-type and mutant p53. This antibody does not work with frozen tissue sections. Cayman’s p53 Monoclonal Antibody (Clone BP53-12) can be used for flow cytometry, immunohistochemistry, immunoprecipitation, and Western blot applications. The antibody recognizes p53 at 53 kDa from human and mouse samples.
宿主来源:
Mouse
实验应用:
FC, IHC (paraffin-embedded tissue), IP, WB; this antibody does not work with frozen tissue sections
同种型:
IgG2a
免疫原:
Recombinant human wild-type p53
克隆号:
BP53-12
保存温度:
-20
运输温度:
-20
产品形式:
100 µg of protein A-affinity purified monoclonal antibody
有效期:
365
来源:
Animal/Mouse
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