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    Nogo-66 (1-40) (human, mouse, rat) (trifluoroacetate salt)
    货号：35310-1 mg 规格：1 mg 目录价：￥560
    货号：35310-10 mg 规格：10 mg 目录价：￥4410
    货号：35310-25 mg 规格：25 mg 目录价：￥9646
    货号：35310-5 mg 规格：5 mg 目录价：￥2492
    产品详情
    产品名称:
    Nogo-66 (1-40) (human, mouse, rat) (trifluoroacetate salt)
    别名:
    NEP1-40|Nogo-40|Nogo-A Inhibitory Peptide|RIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNS-NH2
    产品描述:
    Nogo-66 (1-40) is a peptide fragment of Nogo-A that corresponds to the extracellular domain, Nogo-66, which can induce neurite growth cone collapse in oligodendrocytes.{66166,66167} It is also an antagonist of the Nogo-66 receptor (NgR).{66167} It inhibits binding of the NgR agonist AP-Nogo-66 to, and inhibits growth cone collapse induced by the NgR agonist GST-Nogo-66 in, embryonic day 12 (E12) chick dorsal root ganglia (DRG) explants.{66167} Nogo-66 (1-40) partially reverses axonal outgrowth inhibition induced by purified CNS myelin in E12 chick DRG explants (EC50 = 50 nM). It also induces regeneration of corticospinal tract fibers and improves locomotor function in a rat model of midthoracic spinal cord hemisection injury when administered intrathecally at a dose of 75 µg/kg per day.
    保存温度:
    -20
    运输温度:
    -20
    预期分子量:
    4739.1
    产品形式:
    A solid
    有效期:
    1460
    纯度:
    ≥95%
    分子式:
    C206H324N56O65 • CF3COOH
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