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    Myelin Basic Protein Peptide Antagonist (trifluoroacetate salt)
    品牌:Cayman
    货号:36964-1 mg 规格:1 mg 目录价:¥406
    货号:36964-10 mg 规格:10 mg 目录价:¥3150
    货号:36964-25 mg 规格:25 mg 目录价:¥6888
    货号:36964-5 mg 规格:5 mg 目录价:¥1792
    产品详情
    产品名称:
    Myelin Basic Protein Peptide Antagonist (trifluoroacetate salt)
    别名:
    EKPKVEAYKAAAAPA-OH|MBP Peptide Antagonist
    产品描述:
    Myelin basic protein (MBP) peptide antagonist is a synthetic peptide antagonist against the multiple sclerosis (MS) autoantigen MBP.{64665} MBP peptide antagonist binds to the immunomodulatory region of MBP, corresponding to residues 85-99 and inhibits MBP binding to human HLA-DR2 in a concentration-dependent manner. It inhibits the production of IL-2 in T cell hybridoma cells expressing an MBP (85-99)-specific T cell receptor derived from a patient with multiple sclerosis. MBP peptide antagonist also delays MBP (85-99)-induced experimental autoimmune encephalomyelitis (EAE) onset and reduces EAE symptom severity in double-transgenic humanized mice expressing human HLA-DR2 and MBP (85-99)-specific T cell receptor antigen in a model of MS when administered at a dose of 100 µg/animal.
    保存温度:
    -20
    运输温度:
    -20
    预期分子量:
    1543.8
    产品形式:
    A solid
    有效期:
    1460
    纯度:
    ≥98%
    分子式:
    C70H114N18O21 • XCF3COOH
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