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折扣/货期| 货号：25002 | 规格：5 U | 目录价：￥5530 |
产品详情
产品名称:
LgtC (N. meningitidis) Glycosyltransferase
别名:
Lipopolysaccharyl α-galactosyltransferase|Lipopolysaccharyl-1,4-galactosyltransferase
产品描述:
Lipopolysaccharide α-1,4-galactosyltransferase (LgtC) is a retaining glycosyltransferase and member of glycosyltransferase family 8 (GT8) that is found in N. meningitidis, an opportunistic bacterium that can cause meningitis.{51660} It is composed of an N-terminal mixed α/β domain, which contains the active site, and a C-terminal helical domain, which is responsible for attachment to cell membranes.{51662,51661} LgtC transfers a galactosyl moiety from UDP-galactose (UDP-Gal) to the terminal lactose moiety on lipooligosaccharides (LOSs) while retaining the configuration of the donor sugar glycosidic bond.{51661} Isolated LgtC has been used in the analysis of newborn dried blood spots as a potential screening assay for galactosemia, an inborn error of metabolism characterized by a deficiency in galactose-1-phosphate uridylyltransferase (GALT), the enzyme that converts UDP-glucose to UDP-galactose.{45074} Cayman’s LgtC (N. meningitidis) protein can be used for biocatalysis and enzyme activity assay applications.
保存温度:
-80
运输温度:
-80
产品形式:
50 mM Tris HCl, pH 7.5, with 3 mM DTT
有效期:
365
纯度:
≥90% estimated by SDS-PAGE
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