货号:10007817 | 规格:100 µg | 目录价:¥7042 |
产品详情
产品名称:
Leukotriene A4 Hydrolase (human, recombinant)
别名:
LTA4H
产品描述:
Leukotriene A4 hydrolase (LTA4H) is a bifunctional zinc metalloenzyme that converts LTA4 into LTB4, a potent neutrophil chemoattractant.{12673} In addition to the hydrolase activity, LTA4H also exhibits anion-dependent aminopeptidase activity.{12673,12624} LTA4H is a potential new drug target for a variety of indications associated with leukocyte infiltration to sites of inflammation. Cayman’s LTA4H (human, recombinant) has been expressed and purified from E. coli. Both the epoxide hydrolase and aminopeptidase activities of the enzyme are functional as assessed by measurement of the separate enzyme activities. The enzyme therefore has application for the screening of inhibitors of LTB4 synthesis.
保存温度:
-80
运输温度:
-80
产品形式:
100 mM Tris, pH 8.0, with 100 mM potassium chloride and 20% glycerol
有效期:
365
纯度:
≥90% estimated by SDS-PAGE
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