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JC-10 (high purity)
品牌:Adipogen
货号:AG-CR1-3600-M001 规格:1 mg 目录价:¥780
货号:AG-CR1-3600-M005 规格:5 mg 目录价:¥2340
产品详情
产品名称:
JC-10 (high purity)
别名:
Enhanced JC-1
产品描述:
JC-10 is superior analog of JC-1, useful for determining mitochondrial membrane potential (MMP) in cells by flow cytometry, fluorescence microscopy and in microplate-based fluorescent assays. JC-10 is a cationic, lipophilic dye that accumulates in mitochondria of cells with a polarized mitochondrial membrane, selectively generating an orange J-aggregate emission profile (lambdaex = 540 nm/lambdaem = 590 nm) in healthy cells. Upon cell injury or cell death, as membrane potential decreases, which results in the failure to retain JC-10 aggregates in the mitochondria and JC-10 monomers are generated resulting in a shift to green emission (lambdaex = 490 nm/lambdaem = 525 nm). JC-10 shows improved solubility compared to JC-1 in aqueous media and an ability to detect subtler changes in mitochondrial membrane potential loss. JC-10 allows for qualitative visualization (shift from orange to green fluorescence) and quantitative detection (fluorescence intensity ratio) of mitochondrial membrane potential changes. Wavelength Maxima: lambdaex = 510 nm | lambdaem = 525 nm.
保存温度:
-20°C
运输温度:
Ambient
预期分子量:
~600
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>98% (HPLC)
溶解度:
Soluble in water or DMSO.
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