Interleukin-33 (human) Monoclonal Antibody (Clone IL33305B)-单抗-ELISA_抗体_蛋白_核苷酸

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Interleukin-33 (human) Monoclonal Antibody (Clone IL33305B)

品牌：Cayman

官网链接

说明书

折扣/货期

货号：10809-100 µg	规格：100 µg	目录价：￥5083
货号：10809-50 µg	规格：50 µg	目录价：￥3638

产品详情

产品名称:

Interleukin-33 (human) Monoclonal Antibody (Clone IL33305B)

别名:

IL-1F11|IL-33|NF-HEV

产品描述:

Interleukin-33 (IL-33), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released on cell lysis. The 30 kDa human IL-33 is converted by CASP1 to a 18 kDa protein. IL-33 binds to and signals through ST2 (IL1R1) and its stimulation recruits MYD88, IRAK, IRAK4, and TRAF6, followed by phosphorylation of ERK1 (MAPK3)/ERK2 (MAPK1), p38 (MAPK14), and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells, and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis, asthma, atopic allergy and anaphylaxis, cardiovascular disease/atherosclerosis, nervous system diseases, and sepsis.

宿主来源:

Mouse

实验应用:

ELISA, IHC, IP, and WB

同种型:

IgG2aκ

免疫原:

recombinant human IL-33

克隆号:

IL33305B

保存温度:

-20