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折扣/货期| 货号：CHI-HR-20008-C010 | 规格：10 ug | 目录价：￥2170 |
| 货号：CHI-HR-20008-C050 | 规格：50 ug | 目录价：￥6580 |
产品详情
产品名称:
IL-8 (human) (rec.) (His)
别名:
Interleukin-8; CXCL8; C-X-C Motif Chemokine 8; Emoctakin; GCP-1; LAI; MDNCF; MONAP; NAP-1; NCF; TCF
产品描述:
Interleukin-8 (IL-8) was originally discovered as a neutrophil chemotactic and activating factor and is a member of the alpha (CXC) subfamily of chemokines (including also platelet factor 4, GRO, IP-10, etc.). Many cell types, including monocyte/macrophages, T cells, neutrophils, fibroblasts, endothelial cells, keratinocytes, hepatocytes, chondrocytes and various tumor cell lines, produce IL-8 in response to a wide variety of proinflammatory stimuli such as exposure to IL-1, TNF, LPS and viruses. IL-8 has a wide range of other proinflammatory effects. It is a potent chemoattractant for neutrophils and causes degranulation of neutrophil specific granules and azurophilic granules. IL-8 induces expression of the cell adhesion molecules CD11/CD18 and enhances the adherence of neutrophils to endothelial cells and subendothelial matrix proteins. Besides neutrophils, IL-8 is also chemotactic for basophils, T cells and eosinophils. IL-8 has been reported to be a co-mitogen for keratinocytes and was also shown to be an autocrine growth factor for melanoma cells. IL-8 was also reported to be angiogenic both in vivo and in vitro.
宿主来源:
E. coli
保存温度:
-20°C
运输温度:
BLUE ICE
产品形式:
solid
存储溶液:
Lyophilized from 0.2µm-filtered solution in PBS.
有效期:
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
产地:
瑞士
纯度:
>97% (SDS-PAGE)
内毒素水平:
<0.1EU/µg protein (LAL test; Lonza).
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