货号:CHI-HF-22004-C010 | 规格:10 ug | 目录价:¥2940 |
货号:CHI-HF-22004-C050 | 规格:50 ug | 目录价:¥5040 |
产品详情
产品名称:
IL-4 (human):Fc (human) (rec.) (non-lytic)
别名:
Interleukin-4; B Cell Stimulatory Factor 1; BSF-1
产品描述:
Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to produce IL-2, IFN-gamma, and lymphotoxin (TNF-beta). In addition, mast cells can produce IL-4. IL-4 exerts numerous effects on various hematopoietic cell types. On B cells, IL-4 promotes immunoglobulin class switching to IgE and IgG1 isotypes and upregulates MHC class II and CD23 expression. IL-4 promotes survival, growth, and differentiation of both T and B lymphocytes, mast cells and endothelial cells. In addition, IL-4 inhibits the production of TNF, IL-1, and IL-6 by macrophages.
宿主来源:
CHO cells
保存温度:
-20°C
运输温度:
BLUE ICE
产品形式:
solid
存储溶液:
Lyophilized from 0.2µm-filtered solution in PBS.
有效期:
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
产地:
瑞士
纯度:
>98% (SDS-PAGE)
生物活性:
Shows the biological function of the IL-4 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain.
内毒素水平:
<0.06EU/µg protein (LAL test; Lonza).
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