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    IL-23R (human):Fc (human) (rec.)
    品牌：Adipogen
    货号：CHI-HF-21023R-C100 规格：100 ug 目录价：￥4900
    产品详情
    产品名称:
    IL-23R (human):Fc (human) (rec.)
    别名:
    Interleukin-23 Receptor
    产品描述:
    Interleukin-23 receptor (IL-23R), is a member of the type I cytokine receptor family, type 2 subfamily. It is expressed by monocytes, Th1, Th0, NK and dendritic cells. Isoform 1 is specifically expressed in NK cells. IL-23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL-23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. IL-23R associates with IL-12RB1 to form the interleukin-23 receptor. It binds IL-23 and mediates T cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. Genetic variations in IL-23R are associated with inflammatory bowel disease type 17 (IBD17). IBD17 is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology. Genetic variations in IL-23R also can cause susceptibility to psoriasis type 7.
    宿主来源:
    CHO cells
    保存温度:
    -20°C
    运输温度:
    BLUE ICE
    产品形式:
    solid
    存储溶液:
    Lyophilized from 0.2µm-filtered solution in PBS.
    有效期:
    Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
    产地:
    瑞士
    纯度:
    >98% (SDS-PAGE)
    生物活性:
    Measured by its binding ability in a functional ELISA.
    内毒素水平:
    <0.06EU/µg protein (LAL test; Lonza).
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