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折扣/货期| 货号：CHI-MF-11112-C025 | 规格：25 ug | 目录价：￥5600 |
产品详情
产品名称:
IL-12 (mouse):Fc (human) (rec.)
别名:
IL12-p70; CLMF; Cytotoxic Lymphocyte Maturation Factor; NKSF; Natural Killer Cell Stimulatory Factor; TSF; T cell Stimulating Factor
产品描述:
Interleukin-12 (IL-12), also known as Natural Killer Cell Stimulatory Factor (NKSF) or Cytotoxic Lymphocyte Maturation Factor (CLMF), is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit. IL-12 is produced by macrophages and B lymphocytes and has been shown to have multiple effects on T cells and Natural Killer (NK) cells. Some of these IL-12 activities include the induction of IFN-gamma and TNF in resting and activated T and NK cells; the enhancement of cytotoxic activity of resting NK and T cells, the stimulation of resting T cell proliferation in the presence of a comitogen; and the enhancement of NK cell proliferation. Current evidence indicates that IL-12 is a key mediator of cellular immunity and induces the differentiation of Th1 cells from precursor T helper cells. Based on its activities, it has been suggested that IL-12 may have therapeutic potential as a vaccine adjuvant that promotes cellular immunity and as an antitumor and anti viral agent.
宿主来源:
CHO cells
保存温度:
-20°C
运输温度:
BLUE ICE
预期分子量:
~100-110kDa (SDS-PAGE, reducing conditions)
产品形式:
solid
存储溶液:
Lyophilized from 0.2µm-filtered solution in PBS.
有效期:
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
产地:
瑞士
纯度:
>98% (SDS-PAGE)
内毒素水平:
<0.06EU/µg protein (LAL test; Lonza).
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