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    IL-12 (human):Fc (human) (rec.)
    品牌：Adipogen
    货号：CHI-HF-21012-C025 规格：25 ug 目录价：￥5600
    产品详情
    产品名称:
    IL-12 (human):Fc (human) (rec.)
    别名:
    Interleukin-12; IL-12p70; IL-12p75; Cytotoxic Lymphocyte Maturation Factor; CLMF; NKSF; Natural Killer Cell Stimulatory Factor; TSF; T-cell Stimulatory Factor
    产品描述:
    Interleukin-12 (IL-12), also known as Natural Killer Cell Stimulatory Factor (NKSF) or Cytotoxic Lymphocyte Maturation Factor (CLMF), is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit. IL-12 is produced by macrophages and B lymphocytes and has been shown to have multiple effects on T cells and Natural Killer (NK) cells. Some of these IL-12 activities include the induction of IFN-gamma and TNF in resting and activated T and NK cells; the enhancement of cytotoxic activity of resting NK and T cells, the stimulation of resting T cell proliferation in the presence of a comitogen; and the enhancement of NK cell proliferation. Current evidence indicates that IL-12 is a key mediator of cellular immunity and induces the differentiation of Th1 cells from precursor T helper cells. Based on its activities, it has been suggested that IL-12 may have therapeutic potential as a vaccine adjuvant that promotes cellular immunity and as an antitumor and anti viral agent.
    宿主来源:
    CHO cells
    保存温度:
    -20°C
    运输温度:
    BLUE ICE
    预期分子量:
    ~100-150kDa.
    产品形式:
    solid
    存储溶液:
    Lyophilized from 0.2µm-filtered solution in PBS.
    有效期:
    Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
    产地:
    瑞士
    纯度:
    >98% (SDS-PAGE)
    内毒素水平:
    <1EU/mg protein (LAL test; Lonza).
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