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折扣/货期| 货号：REV-31-1030-MK-KI01 | 规格：1 Set | 目录价：￥7462 |
产品详情
产品名称:
IgA (human) Matched Antibody Pair
别名:
Immunoglobulin A
产品描述:
The Human IgA Matched Antibody Pairs is specific to Human IgA and has been demonstrated through ELISA. It does not cross-react to IgG from Non-Human Primate species (Rhesus and Cynomologus macaques), or mouse, rat or goat immunoglobulin. The kit can be used for the detection of therapeutic antibodies from samples obtained from experimental animals to provide accurate pharmacokinetic (PK) data.Immunoglobulin A (IgA) is an antibody isotype that plays a crucial role in the immune function of mucous membranes. IgA has two subclasses (IgA1 and IgA2) and can be produced as a monomeric as well as a dimeric form. The IgA dimeric form is the most prevalsent and is also called secretory IgA (sIgA). sIgA is the main immunoglobulin found in mucous secretions, including tears, saliva, sweat, colostrum and secretions from the genitourinary tract, gastrointestinal tract, prostate and respiratory epithelium. It is also found in small amounts in blood. The secretory component of sIgA protects the immunoglobulin from being degraded by proteolytic enzymes; thus, sIgA can survive in the harsh gastrointestinal tract environment and provide protection against microbes that multiply in body secretions. In the blood, IgA interacts with the Fc receptor called FcalphaRI (or CD89), which is expressed on immune effector cells, to initiate inflammatory reactions.
靶标/特异性:
The antibody pair detects only human IgA. It does not react to monkey (Cyno or Rhesus) IgG, mouse IgG, rat IgG, or goat IgG. There is no cross reactivity to any other immunoglobulins or IgG subclasses.
保存温度:
-20°C
运输温度:
BLUE ICE
有效期:
Stable for at least 1 year after receipt when stored at -20°C.
产地:
瑞士
检测方法:
Sandwich
样本类型:
Serum
促销活动
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