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    Human PDGF beta protein, His tag (active)
    品牌：GeneTex
    货号：GTX00204-pro 规格：10μg 目录价：￥4000
    产品详情
    产品名称:
    Human PDGF beta protein, His tag (active)
    别名:
    platelet derived growth factor subunit B , IBGC5 , PDGF-2 , PDGF2 , SIS , SSV , c-sis
    实验应用:
    Functional Assay
    克隆号:
    偶联:
    Unconjugated
    产品浓度:
    表达系统:
    E. coli
    保存温度:
    For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, store at -20ºC or below. After reconstitution, keep as concentrated solution. Avoid freeze-thaw cycles.
    运输温度:
    4°C
    产品形式:
    Lyophilized powder
    存储溶液:
    Reconstitute with 20mM Tris and 150mM NaCl to 0.1-1.0mg/ml. Do not vortex. Lyophilized from 20mM Tris, 150mM NaCl, 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose, ProClin 300.
    产地:
    美国
    功能与背景:
    This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit B, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit A. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Mutations in this gene are associated with meningioma. Reciprocal translocationss between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with dermatofibrosarcoma protuberans, a rare skin tumor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
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