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Human p53 protein, His tag
品牌：GeneTex
货号：GTX04503-pro 规格：50μg 目录价：￥7000
产品详情
产品名称:
Human p53 protein, His tag
别名:
tumor protein p53 , BCC7 , BMFS5 , LFS1 , P53 , TRP53
克隆号:
偶联:
Unconjugated
产品浓度:
表达系统:
E. coli
保存温度:
Store at -20ºC or below. After reconstitution, keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
运输温度:
4°C
产品形式:
Lyophilized powder
存储溶液:
Reconstitute with ddH₂O to 0.1-0.2 mg/mL. Do not vortex. Lyophilized from 20mM Tris (pH8.0), 150mM NaCl, 0.01% SKL, 5% Trehalose, no preservatives.
产地:
美国
功能与背景:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
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