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折扣/货期| 货号：GTX02553-pro | 规格：20μg | 目录价：￥3800 |
产品详情
产品名称:
Human MMP7 protein (Active)
别名:
matrix metallopeptidase 7 , MMP-7 , MPSL1 , PUMP-1
实验应用:
Functional Assay
克隆号:
纯化方式:
Purified by proprietary chromatographic techniques
偶联:
Unconjugated
产品浓度:
表达系统:
E. coli
保存温度:
Store as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
运输温度:
dry ice
预期分子量:
30
产品形式:
Liquid
存储溶液:
10mM HEPES, 5mM CaCl₂, 150mM NaCl, no preservative.
产地:
美国
功能与背景:
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers. [provided by RefSeq, Jan 2016]
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