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折扣/货期| 货号：GTX68226-pro | 规格：50μg | 目录价：￥5500 |
产品详情
产品名称:
Human FGFR1OP protein, His tag
别名:
FGFR1 oncogene partner , FOP
克隆号:
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
表达系统:
E. coli
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
dry ice
产品形式:
Liquid
存储溶液:
20mM Tris-HCl, 10% Glycerol, 1mM DTT, no preservative.
产地:
美国
功能与背景:
This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocations, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified. [provided by RefSeq, Jul 2013]
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