货号:GTX68581-pro | 规格:100μg | 目录价:¥5500 |
产品详情
产品名称:
Human DPPA4 protein, His tag
别名:
developmental pluripotency associated 4 , 2410091M23Rik
克隆号:
偶联:
Unconjugated
产品浓度:
0.5 mg/ml (Please refer to the vial label for the specific concentration.)
表达系统:
E. coli
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
dry ice
产品形式:
Liquid
存储溶液:
20mM Tris-HCl, 150mM NaCl, 20% Glycerol, 1mM DTT, no preservative.
产地:
美国
功能与背景:
This gene encodes a nuclear factor that is involved in the maintenance of pluripotency in stem cells and essential for embryogenesis. The encoded protein has a scaffold-attachment factor A/B, acinus and PIAS (SAP) domain that binds DNA and is thought to modify chromatin. Mice with a homozygous knockout of the orthologous gene die during late embryonic development or within hours after birth. Knockout embryos are normal in size at embryonic day 18.5 but exhibit skeletal and lung tissue abnormalities. This gene, when mutated, is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers and is thought to play an important role in tumor progression. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]
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