货号:GTX67834-pro | 规格:100μg | 目录价:¥3300 |
产品详情
产品名称:
Human alpha Synuclein protein
别名:
synuclein alpha , NACP , PARK1 , PARK4 , PD1
克隆号:
偶联:
Unconjugated
产品浓度:
表达系统:
E. coli
保存温度:
Store at -20ºC or below. After reconstitution, keep as concentrated solution. Aliquot and avoid freeze-thaw cycles.
运输温度:
4°C
产品形式:
Lyophilized powder
存储溶液:
Reconstitute with ddH₂O but not less than 100 μg/ml. Lyophilized from 0.2μm-filtered 20mM Tris-HCl buffer (pH7.5), 100mM NaCl, 1mM MgCl₂, no preservative.
产地:
美国
功能与背景:
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]
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