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折扣/货期| 货号：AG-40B-0178-3050 | 规格：3 x 50 ug | 目录价：￥7200 |
| 货号：AG-40B-0178-C050 | 规格：50 ug | 目录价：￥3600 |
产品详情
产品名称:
HpARI (Alarmin Release Inhibitor) (rec.) (His) MultiPack
别名:
Heligmosomoides Polygyrus Alarmin Release Inhibitor
产品描述:
HpARI is a protein secreted by the mouse parasite Heligmosomoides polygyrus. The mature protein HpARI, containing three predicted Complement Control Protein (CCP)-like modules (also known as Short Consensus Repeats (SCRs) or sushi-domains), suppresses type 2 (allergic) immune responses through interference in the interleukin-33 (IL-33) pathway. During cell damage, HpARI gains access to the nucleus of necrotic cells, where it binds directly to IL-33 and nuclear DNA, preventing secretion and binding of IL-33 to its receptor. HpARI is a new type of reagent to prevent IL-33-mediated pathology.
宿主来源:
HEK 293 cells
靶标/特异性:
Binds to human and mouse IL-33.
产品浓度:
After reconstitution: 1mg/ml
保存温度:
-20°C
运输温度:
BLUE ICE
预期分子量:
~40kDa (SDS-PAGE); ~40 kDa (Monomer) (SEC)
产品形式:
solid
存储溶液:
Lyophilized. Contains PBS.
有效期:
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
产地:
瑞士
纯度:
>90% (SDS-PAGE)
内毒素水平:
<0.01EU/µg purified protein (LAL test).
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