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折扣/货期| 货号：11513 | 规格：1 ea | 目录价：￥5922 |
产品详情
产品名称:
HMGB1 Monoclonal Antibody (Clone IMG19N15F4)
别名:
High Mobility Group Protein B1|HMG1
产品描述:
High Mobility Group Protein B1 (HMGB1) belongs to the HMGB family and contains two HMG box DNA-binding domains. It is a highly conserved, ubiquitous protein present in the nuclei and cytoplasm of nearly all cell types, and is a necessary and sufficient mediator of inflammation during sterile and infection-associated responses. HMGB1 also act as DNA nuclear binding protein that has been shown to be an early trigger of sterile inflammation in animal models of trauma-hemorrhage via the activation of the Toll-like receptor 4 (TLR4) and the receptor for the advanced glycation endproducts (RAGE).{20300} It is reported that the level of HMGB1 is elevated during sterile tissue injury, infection, lethal endotoxemia or sepsis, collagen-induced arthritis, and ischemia-reperfusion induced tissue injury.{20304}
宿主来源:
Mouse
实验应用:
FC, IHC (paraffin-embedded tissue), and WB
同种型:
IgG1ĸ
免疫原:
full length recombinant human HMGB1
克隆号:
IMG19N15F4
保存温度:
-20
运输温度:
-20
产品形式:
100 µg of Protein G purified IgG1κ in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide
有效期:
365
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