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折扣/货期| 货号：100034 | 规格：1 ea (500 µl) | 目录价：￥4410 |
产品详情
产品名称:
Goat Anti-COX-2 (human) Affinity-Purified Polyclonal Antibody
别名:
Cyclooxygenase-2|PGHS-2|Prostaglandin H Synthase-2
产品描述:
Cyclooxygenase 2 (COX-2) is a bifunctional enzyme that exhibits both COX and peroxidase activities and catalyzes the first step in the biosesynthesis of prostaglandins, thromboxanes, and prostacyclins.{500,501} The COX component converts arachidonic acid to the hydroperoxy endoperoxide prostaglandin G2 (PGG2; Item No. 17010), and the peroxidase component reduces the endoperoxide to the corresponding alcohol PGH2 (Item No. 17020). COX2 expression is induced by a variety of stimuli, including phorbol esters, LPS, and cytokines and is responsible for the biosesynthesis of PGs under acute inflammatory conditions.{54420,14766} Thus, COX-2 has been the focus of attention for nonsteroidal anti-inflammatory drug (NSAID) development. Cayman's Goat Anti-COX-2 (human) Affinity-Purified Polyclonal Antibody can be used for immunohistochemistry (IHC) and Western blot (WB) applications. The antibody recognizes a unique C-terminal region of COX-2 that is not present in COX-1, specifically detecting COX-2 at 72 kDa from human, mouse, ovine, and rat samples.
宿主来源:
Goat
实验应用:
IHC, WB
免疫原:
Synthetic peptide from the C-terminal region of human COX-2
保存温度:
-20
运输温度:
-20
产品形式:
500 µl of peptide affinity-purified polyclonal antibody
有效期:
1095
来源:
Animal/Goat
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