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Fibrinogen (α chain) Monoclonal Antibody (Clone 6D6)
品牌:Cayman
货号:18793 规格:100 µg 目录价:¥4410
产品详情
产品名称:
Fibrinogen (α chain) Monoclonal Antibody (Clone 6D6)
别名:
FGA
产品描述:
Fibrinogen is a hexameric glycoprotein that has roles in coagulation and hemostasis.{53514,53515} It is comprised of two sets of Aα, Bβ, and γ polypeptide chains encoded by FGA, FGB, and FGG, respectively, in humans.{53514} Fibrinogen is synthesized in hepatocytes and secreted into the plasma. Following thrombin-mediated cleavage of N-terminal fibrinopeptides from the Aα and Bβ chains, yielding the α and β chains, respectively, fibrinogen assembles into fibrin protofibrils and then mature fibers, which provide structure and viscoelasticity to blood clots.{53515,53516,53518} Mutations in FGA, FGB, or FGG have been found in patients with afibrinogenemia or hypofibrinogenemia.{53514} Elevated plasma fibrinogen levels are associated with an increased risk of cardiovascular disease.{53517} Immune complexes containing citrullinated fibrinogen have been found in patients with anti-citrullinated protein antibody-positive rheumatoid arthritis.{21643} Cayman’s Fibrinogen (α chain) Monoclonal Antibody (Clone 6D6) can be used for Western blot (WB) applications. The antibody recognizes the α chain of fibrinogen at 70 kDa from human samples.
宿主来源:
Mouse
实验应用:
WB
同种型:
IgG1
免疫原:
Human fibrinogen (α chain)
克隆号:
6D6
保存温度:
-20
运输温度:
-20
产品形式:
100 µg of protein G-purified antibody
有效期:
1095
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