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    F1 (trifluoroacetate salt)
    品牌:Cayman
    货号:35846-1 mg 规格:1 mg 目录价:¥364
    货号:35846-10 mg 规格:10 mg 目录价:¥2856
    货号:35846-25 mg 规格:25 mg 目录价:¥6258
    货号:35846-5 mg 规格:5 mg 目录价:¥1624
    产品详情
    产品名称:
    F1 (trifluoroacetate salt)
    别名:
    Tat-IKIP (46-60)|Tat-Inhibitor of NF-κB Kinase-interacting Peptide
    产品描述:
    F1 is an anti-inflammatory peptide composed of the HIV-1 Tat protein transduction domain linked to a 15-amino acid peptide corresponding to residues 46-60 of inhibitor of NF-κB kinase-interacting peptide (IKIP).{66515} It inhibits LPS-induced phosphorylation of IκB kinase α (IKKα) and IKKβ and nuclear translocations of NF-κB (p65) in isolated mouse peritoneal macrophages when used at a concentration of 5 µM. In vivo, F1 (5 mg/kg) decreases serum levels of IL-6, TNF-α, and IL-1β and increases survival in a mouse model of LPS-induced sepsis.
    保存温度:
    -20
    运输温度:
    -20
    预期分子量:
    3189.9
    产品形式:
    A solid
    有效期:
    1460
    纯度:
    ≥98%
    分子式:
    C145H246N48O31S • XCF3COOH
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