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DNA Monoclonal Antibody (Clone 4E9)
品牌:Cayman
货号:30185 规格:100 µg 目录价:¥5600
产品详情
产品名称:
DNA Monoclonal Antibody (Clone 4E9)
别名:
DNA Antibody|ss/dsDNA Monoclonal Antibody
产品描述:
Activated neutrophils produce neutrophil extracellular traps (NETs), antimicrobial snares that are comprised of granular and cytoplasmic proteins, as well as decondensed nuclear DNA associated with histone proteins.{53539} NET degradation is impaired in patients with systemic lupus erythematosus (SLE), allowing for production of autoantibodies against NET components, including dsDNA. The NZBWF1 mouse model of SLE similarly produces autoantibodies against chromatin, dsDNA, and ssDNA.{53540,53541} Cayman's DNA Monoclonal Antibody (Clone 4E9) was developed by fusing the spleen of a non-immunized NZBWF1 mouse with a mouse myeloma cell line and can be used for immunohistochemistry (IHC), immunofluorescence (IF), and ELISA applications. The antibody recognizes ssDNA and dsDNA, including nuclear DNA, from human and bovine samples.
宿主来源:
Mouse
实验应用:
IHC, IF, ELISA
同种型:
IgG1
克隆号:
4000000000
保存温度:
-20
运输温度:
-20
产品形式:
100 µg of protein G-purified monoclonal antibody
有效期:
1095
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