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Dibenzylfluorescein
品牌:Adipogen
货号:CDX-D0282-M100 规格:100 mg 目录价:¥2660
货号:CDX-D0282-M500 规格:500 mg 目录价:¥7098
产品详情
产品名称:
Dibenzylfluorescein
别名:
DBF; NSC 645658
产品描述:
Dibenzylfluorescein is a fluorogenic probe that acts as a substrate for specific cytochrome P450 (CYP) isoforms, including CYP3A4, CYP2C8, CYP2C9, CYP2C19 and aromatase (CYP19). It is dealkylated by these CYP isoforms to produce fluorescein benzyl ether, which is further hydrolyzed to fluorescein by the addition of base (typically 2 M NaOH). Dibenzylfluorescein is typically used near its apparent Km value of 0.87-1.9 µM. The fluorescence of fluorescein is evalsuated using excitation/emission wavelengths of 485/538nm. Dibenzylfluorescein is used to detect changes in CYP catalytic activity caused by drugs or disease.
宿主来源:
Synthetic
保存温度:
-20°C
运输温度:
Ambient
预期分子量:
512.55
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>98% (NMR)
CAS号:
97744-44-0
分子式:
C34H24O5
溶解度:
Soluble in DMSO (10mg/ml) or DMF (20mg/ml).
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