货号:V9406SAF-100UG | 规格:100 ug | 目录价:¥6176.1 |
产品详情
产品名称:
DC-SIGN Antibody / CD209
产品描述:
DC-SIGN/CD209 is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity.
反应种属:
Human
宿主来源:
Mouse
实验应用:
FACS
同种型:
Mouse IgG1, kappa
免疫原:
A recombinant human DC-SIGN/CD209 protein fragment was used as the immunogen for the CD209 antibody.
克隆性:
Monoclonal (mouse origin)
纯化方式:
Protein A/G affinity
保存温度:
Aliquot the CD209 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
存储溶液:
1 mg/ml in 1X PBS; BSA free, sodium azide free
产地:
美国
生产商:
NSJ Bio
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