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折扣/货期| 货号：CDX-B0307-M100 | 规格：100 mg | 目录价：￥1064 |
产品详情
产品名称:
D-Biotin p-nitrophenyl ester
别名:
(+)-Biotin 4-nitrophenyl ester; 4-Nitrophenyl (+)-biotinate; BNP; Biotin-ONp
产品描述:
(+)-Biotin 4-nitrophenyl ester (Biotin-ONp) is a pre-activated biotin derivative, that is used as a biotinylation reagent in the modification of peptides, amino acids and proteins. Biotin-ONp is an effective and efficient tool for the introduction of biotin during solid phase synthesis, offering greater reactivity and higher solubility than Biotin-OSu. It may also be used to prepare biotinylated quinazoline derivatives. Recently, Biotin-ONp has been described as an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
宿主来源:
Synthetic
保存温度:
-20°C
运输温度:
Ambient
预期分子量:
365.4
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
33755-53-2
分子式:
C16H19N3O5S
溶解度:
Soluble in methanol (25mg/ml).
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