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折扣/货期| 货号：CDX-D0189-M250 | 规格：250 mg | 目录价：￥1330 |
产品详情
产品名称:
Dansylcadaverine
别名:
N-(5-Aminopentyl)-5-dimethylaminonaphthalene-1-sulfonamide; N-(Dimethylaminonaphthalenesulfonyl)-1,5-pentanediamine; MDC; Monodansyl cadaverine
产品描述:
Fluorescent probe for derivatization of aldehydes, ketones and carboxylic acids. Used to prepare small fluorescent biomolecules via amidation or reductive amination. Used to monitor autophagy. Functions by marking the autophagosomes, which allows researchers to follow the molecular components of the process throughout. Accumulates in autophagic vacuoles due to a combination of ion trapping and specific interactions with membrane lipids. Has biological applications in measuring cardiac autophagic flux, studying Parkinson's disease, peritoneal ovarian tumor dissemination and respiratory diseases. This fluorescent tag is preferred over other due to its specificity and simplicity in detecting autophagic vesicles. Fluorescent substrate for assaying transamidating enzymes. Shown to inhibit endocytosis, the fibrin-stabilizing factor and epidermal growth factor (EGF) internalization. Dansyl dyes have environmentally sensitive fluorescence quantum yields and emission maxima along with large stokes shifts. Spectral Data: lambdaex 335nm; lambdaem518 nm in methanol.
宿主来源:
Synthetic.
保存温度:
-20°C
运输温度:
Ambient
预期分子量:
335.46
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>98% (NMR)
CAS号:
10121-91-2
分子式:
C17H25N3O2S
溶解度:
Soluble in methanol or DMSO.
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