官网链接
折扣/货期| 货号：SKT-217-192 | 规格：96 well x2 | 目录价：￥3348 |
产品详情
产品名称:
Creatinine Serum Detection Kit
别名:
N-Carbamimidoyl-N-methylglycine Detection Kit, Methylguanidoacetic acid Detection Kit
产品描述:
Colorimetric measurement of creatinine
反应种属:
Human | Mouse | Rabbit | Rat | Sheep
保存温度:
4ºC
运输温度:
Blue Ice
产地:
加拿大
功能与背景:
Creatinine (2-amino-1-methyl-5H-imadazol-4-one) is a metabolite of phosphocreatine (p-creatine), a molecule used as a store for high-energy phosphate that can be utilized by tissues for the production of ATP (1). Creatine either comes from the diet or synthesized from the amino acids arginine, glycine, and methionine. This occurs in the kidneys and liver, although other organ systems may be involved and species-specific differences may exist (2). Creatine and p-creatine are converted non-enzymatically to the metabolite creatinine, which diffuses into the blood and is excreted by the kidneys.
In vivo , this conversion appears to be irreversible and in vitro it is favored by higher temperatures and lower pH2. Creatinine forms spontaneously from p-creatine (3). Under normal conditions, its formation occurs at a rate that is relatively constant and as intra-
individual variation is <15% from day to day, creatinine is a useful tool for normalizing the levels of other molecules found in urine. Additionally altered creatinine levels may be associated with other conditions that result in decreased renal blood flow such as diabetes and cardiovascular disease (4-6).
灵敏度:
0.085 mg/dl
检测范围:
0.5 - 4 mg/dl
检测方法:
Direct
样本类型:
Serum | Plasma
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