货号:29262 | 规格:100 µl | 目录价:¥8064 |
产品详情
产品名称:
c-Fos Monoclonal Antibody
别名:
AP-1 Transcription Factor Subunit|FBJ Murine Osteosarcoma Viral Oncogene Homolog|Fos Proto-oncogene|Proto-oncogene c-Fos
产品描述:
c-Fos is a widely expressed nuclear protein and member of the Fos protein family that includes c-Fos, FosB, Fra-1, and Fra-2.{55194} It is a proto-oncogene that contains a leucine zipper motif to facilitate heterodimerization with Jun family proteins, such as c-Jun, to form the transcription factor complex activator protein-1 (AP-1) that has roles in cell proliferation, differentiation, and apoptosis. Expression of c-fos is induced in response to growth factors, tumor promoters, cytokines, and UV radiation.{55194,55195} In neurons, c-fos expression is induced upon depolarization and is widely used as a marker of neuronal activation.{55196} c-fos is also overexpressed in a variety of tumor cells, and transgenic overexpression of c-fos in mice induces formation of chondrosarcomas.{55195,55197} Cayman's c-Fos Monoclonal Antibody can be used for immunocytochemistry (ICC), immunohistochemistry (IHC), and Western blot (WB) applications. The antibody recognizes c-Fos at approximately 50 kDa from human, bovine, mouse, and rat samples.
宿主来源:
Mouse
实验应用:
ICC, IHC, WB
免疫原:
Recombinant human full-length c-Fos
保存温度:
-20
运输温度:
-20
产品形式:
100 µl of protein G-purified monoclonal antibody
有效期:
365
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