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CCL4 (human):Fc (human) (rec.)
品牌：Adipogen
货号：CHI-HF-210CCL4-C050 规格：50 ug 目录价：￥3500
产品详情
产品名称:
CCL4 (human):Fc (human) (rec.)
别名:
C-C Motif Chemokine 4; Lymphocyte Activation Gene 1 Protein; LAG-1; Macrophage Inflammatory Protein 1beta; MIP-1beta; T Cell Activation Protein 2; ACT-2; Small-inducible Cytokine A4; PAT 744; Protein H400
产品描述:
CCL4, (C-C motif chemokine 4; macrophage inflammatory protein 1beta) is a chemokine secreted at sites of inflammation by activated leukocytes, lymphocytes, vascular endothelial cells and pulmonary smooth cells. CCL4 attracts a variety of immune cells to sites of microbial infection as well as to pathologic inflammation, such as allergic asthma and ischemic myocardium. Full-length and truncated CCL4 exert biological activity through the receptor CCR5. The truncated form of CCL4 interacts additionally with CCR1 and CCR2b. The ability of CCL4 to bind CCR5 inhibits the cellular entry of M-tropic HIV. Both CCL4 forms block HIV-1 infection of T cells by inducing the downregulation of CCR5.
宿主来源:
CHO cells
保存温度:
-20°C
运输温度:
BLUE ICE
产品形式:
solid
存储溶液:
Lyophilized from 0.2µm-filtered solution in PBS.
有效期:
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
产地:
瑞士
纯度:
>98% (SDS-PAGE)
内毒素水平:
<0.06EU/µg protein (LAL test; Lonza).
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