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Caspase-14 Monoclonal Antibody (Clone 70A1426)
货号:13916 规格:1 ea 目录价:¥6048
产品详情
产品名称:
Caspase-14 Monoclonal Antibody (Clone 70A1426)
产品描述:
Caspases are a family of cysteine proteases that are key mediators of programmed cell death or apoptosis.{18384} The precursor form of all caspases is composed of a prodomain and large and small catalytic subunits. The active forms of caspases are generated by several stimuli including ligand-receptor interactions, growth factor deprivation, and inhibitors of cellular functions. All known caspases require cleavage adjacent to aspartates to liberate one large and one small subunit, which associate into an a2b2 tetramer to form the active enzyme. Caspase-14 has a conserved active site pentapeptide, QACRG. However, no proteolytic or biological activities have been identified so far. Its high expression in embryonic tissues and limited expression in adult tissues suggests that it may have some role during ontogenesis.
宿主来源:
Mouse
实验应用:
FC (intracellular) and WB
免疫原:
Synthetic peptide corresponding to mouse caspase-14 amino acids 2-18
克隆号:
70A1426
保存温度:
-20
运输温度:
-20
产品形式:
200 µl antibody solution containing 0.09% sodium azide
有效期:
180
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