Calcein-AM solution (4 mM in DMSO), 1 mg in 0.25 ml DMSO-细胞染料及荧光探针-深圳九游会j9网站首页有限公司

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Calcein-AM solution (4 mM in DMSO), 1 mg in 0.25 ml DMSO

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：CDX-C0686-M001

规格：1 mg

目录价：￥6398

产品详情

产品名称:

Calcein-AM solution (4 mM in DMSO), 1 mg in 0.25 ml DMSO

别名:

CAL-AM; Calcein Acetoxymethyl ester; NSC 689290

产品描述:

Calcein AM is a non-fluorescent cell permeable and hydrophobic probe that, upon entering live cells, is cleaved by intracellular esterases, releasing the membrane-impermeable, hydrophilic, and intensely bright green fluorescent calcein. Better retained by viable cells than fluorescein, carboxyfluorescein, or BCECF, due to its low cytotoxicity. It can be used as an indicator of cell viability (dead cells lack cytoplasmic esterases), cell-cell communication, cytotoxicity or changes in intracellular calcium, fluoride, iron or mercury. Calcein-AM is a neutral substrate for multidrug resistance-associated protein 1 (MRP1) and multidrug resistance protein 3 (MDR3, P-glycoprotein 3) and has been used in flow cytometry studies to analyze the function of P-gp and MRP. Used as a cytosolic fluorophore in mitochondrial permeability studies to image pore transition. Viability assays using calcein are reliable and correlate well with the standard 51Cr-release assay. Spectral Data: lambdaEx 496nm, lambdaEm 516nm in 0.1M Tris pH 8.0.

宿主来源:

Synthetic

产品浓度:

4mM in DMSO (1 mg in 0.25ml DMSO)

保存温度:

-20°C

运输温度:

预期分子量:

994.86

产品形式:

liquid

有效期: