货号:38848-1 mg | 规格:1 mg | 目录价:¥364 |
货号:38848-10 mg | 规格:10 mg | 目录价:¥2856 |
货号:38848-25 mg | 规格:25 mg | 目录价:¥6258 |
货号:38848-5 mg | 规格:5 mg | 目录价:¥1624 |
产品详情
产品名称:
BRC4wt (trifluoroacetate salt)
产品描述:
BRC4wt is an acetylated peptide derived from the BRC4 repeat in human BRCA2 (1521-1536) and an inhibitor of the protein-protein interaction between BRCA2 and RAD51.{66463} When coupled to the cationic cell-penetrating peptide (Arg)9 (Item No. 36714), BRC4wt shortens DNA replication tract lengths and reduces homologous repair frequency of DNA damage induced by the DNA topoisomerase I inhibitor camptothecin (Item No. 11694) in vitro, as well as potentiates cell death induced by the poly(ADP-ribose) polymerase (PARP) inhibitor olaparib (Item No. 10621) in HeLa human cervical cancer and U2OS human osteosarcoma cells but not in non-cancerous hTERT RPE-1, MRC-5, or MCF-10A cells.
保存温度:
-20
运输温度:
-20
预期分子量:
1739.1
产品形式:
A solid
有效期:
1460
纯度:
≥98%
分子式:
C81H139N23O19 • XCF3COOH
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